--- title: "Case Study Abstract: Efficacy of low-level laser therapy applied at acupuncture points in knee osteoarthritis: a randomized double-blind comparative trial" description: "Forty-nine patients with knee osteoarthritis were assigned at random into two groups: active laser group (n=26) and placebo laser group (n=23)." image: https://blog.celasers.com/hubfs/Blog%20Image%20Assets/knee%20osteoarthritis.jpeg --- [![Cutting Edge Laser Technologies Logo](https://blog.celasers.com/hs-fs/hubfs/CuttingEdge_September2018/Images/logo.png?width=200&name=logo.png "Cutting Edge Laser Technologies Logo")](https://celasers.com/) # Laser Therapy & Orthopedics # Case Study Abstract: Efficacy of low-level laser therapy applied at acupuncture points in knee osteoarthritis: a randomized double-blind comparative trial Posted by [Chrissy Laughlin](https://blog.celasers.com/med/author/chrissy-laughlin) on Aug 25, 2017 1:08:32 PM - [Tweet](https://twitter.com/share) Original Abstract can be viewed [here](https://www.ncbi.nlm.nih.gov/pubmed/24418801) #### **OBJECTIVE:** To evaluate the efficacy of low-level laser therapy (LLLT) applied to acupuncture points on the knee joint in combination with exercise and advice in patients with knee osteoarthritis. #### **DESIGN**: Randomised, double-blind, comparative clinical trial. #### **PARTICIPANTS:** Forty-nine patients with knee osteoarthritis were assigned at random into two groups: active laser group (n=26) and placebo laser group (n=23). #### **INTERVENTION:** Using a gallium aluminium arsenide laser device, patients received either active or placebo LLLT at five acupuncture points on the affected knee during nine sessions. #### **OUTCOME MEASURES:** Patients were assessed using a visual analogue scale (VAS) and the Saudi Knee Function Scale (SKFS) at baseline, the fifth treatment session, the last treatment session, 6 weeks post intervention and 6 months post intervention. #### **RESULTS:** VAS scores showed a significant improvement in the active laser group compared with the placebo laser group at 6 weeks post intervention [mean difference -1.3, 95% confidence interval (CI) of the difference -2.4 to -0.3; P=0.014] and 6 months post intervention (mean difference -1.8, 95% CI of the difference -3.0 to -0.7; P=0.003) using the independent samples test. SKFS scores also showed a significant improvement in the active laser group compared with the placebo laser group at the last treatment session (median difference -15, 95% CI of the difference -27 to -2; P=0.035) and 6 months post intervention (median difference -21, 95% CI of the difference -34 to -7; P=0.006) using the Mann-Whitney U test. #### **CONCLUSIONS:** The results demonstrate that short-term application of LLLT to specific acupuncture points in association with exercise and advice is effective in reducing pain and improving quality of life in patients with knee osteoarthritis. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved. ![knee osteoarthritis.jpeg](https://blog.celasers.com/hubfs/Blog%20Image%20Assets/knee%20osteoarthritis.jpeg) #### **KEYWORDS:** Acupuncture for knee joint; Laser acupuncture; Laser therapy; Low-level laser therapy (LLLT); Osteoarthritis of knee; Phototherapy [Al Rashoud AS](https://www.ncbi.nlm.nih.gov/pubmed/?term=Al%20Rashoud%20AS%5BAuthor%5D&cauthor=true&cauthor_uid=24418801)1, [Abboud RJ](https://www.ncbi.nlm.nih.gov/pubmed/?term=Abboud%20RJ%5BAuthor%5D&cauthor=true&cauthor_uid=24418801)1, [Wang W](https://www.ncbi.nlm.nih.gov/pubmed/?term=Wang%20W%5BAuthor%5D&cauthor=true&cauthor_uid=24418801)1, [Wigderowitz C](https://www.ncbi.nlm.nih.gov/pubmed/?term=Wigderowitz%20C%5BAuthor%5D&cauthor=true&cauthor_uid=24418801)2. ### [Author information](https://www.ncbi.nlm.nih.gov/pubmed/24418801#) 1 Institute of Motion Analysis and Research, Department of Orthopaedic and Trauma Surgery, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK. 2 Institute of Motion Analysis and Research, Department of Orthopaedic and Trauma Surgery, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK. Electronic address: c.a.wigderowitz@dundee.ac.uk.   Topics: [Knee Osteoarthritis](https://blog.celasers.com/med/topic/knee-osteoarthritis) **About Our Blog** Our blog focuses on providing relevant educational content as a resource for laser therapy users. Since our founding in 2001, our mission has remained the same; to provide high value medical equipment to healthcare professionals that will improve the quality of medicine practiced while improving their bottom line. ### Subscribe To Our Blog ### Recent Posts ### Posts by Topic - [Class IV Laser (7)](https://blog.celasers.com/podiatry/topic/class-iv-laser) - [MLS Laser Therapy (7)](https://blog.celasers.com/podiatry/topic/mls-laser-therapy) - [Laser Therapy for Podiatry (5)](https://blog.celasers.com/podiatry/topic/laser-therapy-for-podiatry) - [Laser Therapy (4)](https://blog.celasers.com/podiatry/topic/laser-therapy) - [Ligament and Tendon Injuries (4)](https://blog.celasers.com/podiatry/topic/ligament-and-tendon-injuries) - [Podiatry (4)](https://blog.celasers.com/podiatry/topic/podiatry) - [Anti-Inflammatory (3)](https://blog.celasers.com/podiatry/topic/anti-inflammatory) - [High Intensity Laser Therapy (3)](https://blog.celasers.com/podiatry/topic/high-intensity-laser-therapy) - [Photochemical Effect (3)](https://blog.celasers.com/podiatry/topic/photochemical-effect) - [Photomechanical Effect (3)](https://blog.celasers.com/podiatry/topic/photomechanical-effect) - [Photothermal Effect (3)](https://blog.celasers.com/podiatry/topic/photothermal-effect) - [Plantar Fasciitis (3)](https://blog.celasers.com/podiatry/topic/plantar-fasciitis) - [Clinical Benefits of Laser Therapy (2)](https://blog.celasers.com/podiatry/topic/clinical-benefits-of-laser-therapy) - [Degenerative Joint Conditions (2)](https://blog.celasers.com/podiatry/topic/degenerative-joint-conditions) - [HILT (2)](https://blog.celasers.com/podiatry/topic/hilt) - [Heel Pain (2)](https://blog.celasers.com/podiatry/topic/heel-pain) - [Laser Therapy Benefits (2)](https://blog.celasers.com/podiatry/topic/laser-therapy-benefits) - [Neuromas (2)](https://blog.celasers.com/podiatry/topic/neuromas) - [Robotic Laser (2)](https://blog.celasers.com/podiatry/topic/robotic-laser) - [Therapeutic Laser (2)](https://blog.celasers.com/podiatry/topic/therapeutic-laser) - [Wound Healing (2)](https://blog.celasers.com/podiatry/topic/wound-healing) - [Achilles Tendinitis (1)](https://blog.celasers.com/podiatry/topic/achilles-tendinitis) - [Arthritic Conditions (1)](https://blog.celasers.com/podiatry/topic/arthritic-conditions) - [Arthritis (1)](https://blog.celasers.com/podiatry/topic/arthritis) - [Chronic Pain (1)](https://blog.celasers.com/podiatry/topic/chronic-pain) - [Class 3B Laser (1)](https://blog.celasers.com/podiatry/topic/class-3b-laser) - [Diabetes (1)](https://blog.celasers.com/podiatry/topic/diabetes) - [Knee Osteoarthritis (1)](https://blog.celasers.com/podiatry/topic/knee-osteoarthritis) - [LLLT (1)](https://blog.celasers.com/podiatry/topic/lllt) - [M6 Laser (1)](https://blog.celasers.com/podiatry/topic/m6-laser) - [MLS Class IV Laser (1)](https://blog.celasers.com/podiatry/topic/mls-class-iv-laser) - [Muscle Strains (1)](https://blog.celasers.com/podiatry/topic/muscle-strains) - [Nd:YAG (1)](https://blog.celasers.com/podiatry/topic/ndyag) - [Neuropathy (1)](https://blog.celasers.com/podiatry/topic/neuropathy) - [Patient (1)](https://blog.celasers.com/podiatry/topic/patient) - [Post-Op Pain & Scarring (1)](https://blog.celasers.com/podiatry/topic/post-op-pain-scarring) - [Price (1)](https://blog.celasers.com/podiatry/topic/price) - [Reduced Pain (1)](https://blog.celasers.com/podiatry/topic/reduced-pain) - [Revenue (1)](https://blog.celasers.com/podiatry/topic/revenue) - [Sesamoiditis (1)](https://blog.celasers.com/podiatry/topic/sesamoiditis) - [Tendon and Ligament Injuries (1)](https://blog.celasers.com/podiatry/topic/tendon-and-ligament-injuries) - [Vascular Activity (1)](https://blog.celasers.com/podiatry/topic/vascular-activity) [see all](https://blog.celasers.com/med/abstract-efficacy-of-low-level-laser-therapy-applied-at-acupuncture-points-in-knee-osteoarthritis#) - [**](https://www.facebook.com/CELasers) - [**](https://twitter.com/CELasers) - [**](https://www.youtube.com/user/CuttingEdgeLasers) - [**](https://www.linkedin.com/company/cutting-edge-lasers-inc-) 50 Methodist Hill Drive | Suite 600 | Rochester| NY | 14623-4268 © 2018 Cutting Edge Laser Technologies | Therapy Lasers | Surgical Lasers All rights reserved | [Site Map](http://www.celasers.com/sitemap) | Site developed by [Mason Digital](http://www.masondigital.com) 800.889.4184 **[MORE INFO](http://www.celasers.com/component/rsform/form/5-request-medical-information?Itemid=254) | [DEMO](http://www.celasers.com/component/rsform/form/4-schedule-a-medical-demo?Itemid=243)**